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Hepatoprotective effect of annona muricata, allium sativa, curcuma mangga, and ananas comosus in rat after ccl4 induction

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Liver has a function to neutralizing toxic substances that enter the body causing it as a main target for toxicity. Natural products like soursop, garlic, white turmeric and pineapple is the 4 main things that have been studied for their hepatoprotective properties. This research was to determine the dose and hepatoprotective characteristic of the 4 extracts. The hepatoprotective activity of the extract was determined by measuring serum glutamic-oxaloacetic transaminase (SGPT), serum glutamic-pyruvic transaminase (SGOT) and A/G ratio level on rat blood. There were 24 rats prepared, divided into 4 groups; control, negative control (untreated group), and 2 treated groups and each was given the extract with certain dose and 3 times of dose from the otherrngroup. Treatment was conducted for 6 weeks. Rat blood was collected 4 times. Before CCl4 injection, after CCl4 injection and 3 weeks after the extract was given to the rats. Data Analysis test that was used in the experiment was One-Way ANOVA using SPSS with 95% confidence interval. Based on the results, the combination of 4 extracts can reduced the SGOT and SGPT levels and increase the A/G Ratio levels on treated experimental subject (rats) after being induced with CCl4.

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Availability

B03129

(Rack Thesis)

Available

Detail Information

Series Title

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Call Number

3129

Publisher

: Swiss German University., 2019

Collation

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Language

English

ISBN/ISSN

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Classification

NONE

Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

BE
Pineapple
Annona muricata
Ananas comosus
hepatoprotective
Soursop Leaves
Garlic
Allium Sativa
White Turmeric
Curcuma Mangga

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