Molecular binding study of tetra-hydroxyl-ethyl-disulphate-2-sodium (thes) as a non-resistant antibacterial agent

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Molecular binding study of tetra-hydroxyl-ethyl-disulphate-2-sodium (thes) as a non-resistant antibacterial agent

Development on novel therapeutic agents and drugs is important to combat multidrug resistant bacterial infections. This study investigates molecular mechanism of Tetra-hydroxyl-ethyl-disulphate-2-sodium (THES) as a non-resistant bacterial agent with bactericidal properties against Gram-positive and Gram-negative bacteria. Isothermal titration calorimetry (ITC) technique was utilized to measure properties of binding between bacterial peptidoglycan and THES agent. The measurements were designed to verify the proposed mechanism of THES

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B02654 (Rack Thesis) Available

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Series Title: -
Call Number: 2654
Publisher: : Swiss German University., 2017
Collation: -
Language: English
ISBN/ISSN: -
Classification: NONE
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Statement of Responsibility: verifying the proposed mechanism with dissociation value of 17.5 M. The study also provides visual evidence of THES mechanism on bacterial wall. Three-dimensional and cross-section measurement taken

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