Ginger juice concentrate as wetting agent in wet granulation process of traditional pharmaceutical for common cold (Jamu Tolak Angin)

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Ginger juice concentrate as wetting agent in wet granulation process of traditional pharmaceutical for common cold (Jamu Tolak Angin)

Ardhiyanto, Mario - Personal Name; Kartawiria, Irvan S. - Personal Name;

The aim of this research was to evaluate the ginger juice performance as wetting agent in wet granulation process of traditional pharmaceuticals for common cold (jamu tolak angin). In this research, ginger juice was made from red ginger. There are eight formulas to determine the effects of ginger juice in wet granulation process. Experiments were done into two steps, granulation and tablet compression process with analyses during its steps. Average particle size distribution of granules is 0.23 ? 1.63, Carr?s index is 4.50 % ? 41.00 %. Tablet performance was observed by comparing tablet weight, hardness, and disintegration time. Tablet weight is 540 - 627 mg, with hardness 8.46 ? 14.78 kp and disintegration time below 300 s. The feasible formula was batch which contained maximum ginger juice content without binder. Its appearance and performance of the batch were superior to other batches.

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Series Title: -
Call Number: 615
Publisher: : Swiss German University., 2009
Collation: -
Language: English
ISBN/ISSN: -
Classification: NONE
Content Type: -
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Edition: -
Subject(s): PE
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