Spray drying process for bitter melon (momordica charantia) extract to produce instant anti-diabetic drink
Diabetes mellitus is a serious illness faced by many people including in Indonesia. Inhibitor of ?-Glucosidase enzyme is one way to control blood glucose level in the human body. Momordica charantia or bitter melon which also known as paria, has long been used to treat diabetics due to its hypoglycaemic properties as it serves as ?-glucosidase inhibitor. This research was aimed to produce anti-diabetic instant drink from bitter melon extract through spray drying process. Prior to spray drying, the dried bitter melon was extracted using 50% ethanol as solvent. The parameter used was the activity of the extract as inhibitor to ?- glucosidase enzyme. The higher the inhibition activity, the more hypoglycaemic it was. This research had successfully produced an anti-diabetic instant drink from bitter melon extract with IC50 to ?-glucosidase enzyme of 0.20 g/ml.
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