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Application of spray dried butterfly pea root extract to lowering acethylcholinesterase levels on animal models

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Butterfly Pea or Clitoria ternatea is a decorative plant found throughout Southeast Asia and India. Though mostly used as a decoration it has been used for a variety of medical symptomps. One of these symptom is Alzheimer’s which is marked with the increase of Acetylcholinesterase enzyme level in the brain and blood. While it is proven that the extract does inhibit the Acetylcholinesterase production only small amounts of the extract can be made at a time. A new method of extraction using a spray dryer is used to create larger amounts of the Extract but with lower concentrations compared to the traditional technique of freeze drying extraction. To learn if the Lower concentration can still effectively treat Alzheimer’s this experiment was done. The Alzheimer’s disease in this experiment are induced using high amounts of scopolamine. While there were significant difference before and after the treatment the decrease of the acetylcholinesterase levels are insignificant between the groups. The results prompted a scientific guess whereas the decrease of acetylcholinesterase levels in the rats are naturally occurring phenomenon. At the same time the data shows potential that the treatment and the dosage maybe the key to getting better results."

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Availability

B02277

2277

(Rack Thesis)

Available

Detail Information

Series Title

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Call Number

2277

Publisher

mou : Swiss German University., 2016

Collation

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Language

English

ISBN/ISSN

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Classification

NONE

Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

Food technology
FT
Clitoria ternatea
Butterfly pea root
Alzheimer’s Disease
Acetylcholinesterase enzyme
Root Extraction

Specific Detail Info

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Statement of Responsibility

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